New Covid variant: How worried should we be? – BBC News

In a media briefing Prof de Oliveira said there were 50 mutations overall and more than 30 on the spike protein, which is the target of most vaccines and the key the virus uses to unlock the doorway into our body’s cells.

Zooming in even further to the receptor binding domain (that’s the part of the virus that makes first contact with our body’s cells), it has 10
mutations compared to just two for the Delta variant …

This level of mutation has most likely come from a single patient who was unable to beat the virus.